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Prevention of CVD - From Epidemiology to Guidelines and Policies

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Dr Pamela Morris, USA    04 January 2018

  1. The 2017 focused update of 2016 ACC EDCP address four statin benefit groups: Adults ≥21 years of age with clinical ASCVD on statin for secondary prevention; or with LDL-C ≥190 mg/dL on statin for primary prevention; adults aged 45-70 years without ASCVD but with diabetes and LDL-C 70-189 mg/dL on statin for primary prevention; or without clinical ASCVD or diabetes, with LDL-C 70-189 mg/dL and an estimated 10-year risk for ASCVD of ≥7.5% on statin for primary prevention.
  2. LAI 2016: Nonstatin drugs are recommended to be used in case of complete statin intolerance; first-line therapy when TG >500 mg/dL; in combination with statins when desired statin dose is not tolerated or in persistent hypertriglyceridemia.

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